Impressive Regeneration To Repair Large Bone Injuries

[ad_1] AMer surgical rib resection (top), a cartilage and bone bridge form (second from top) and then resolve (third from top) and remodel to regenerate the missing tissue in the gap (boQom). Blue shows cartilage matrix; red shows mineralized matrix. Credit: Images by Stephanie Kuwahara and Max Serowoky, Mariani Lab A stem cell study presents […]

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New Hope for Treatment of Parkinson’s Disease: Designer Neurons

[ad_1] The new research describes the implantation of induced pluripotent stem cells (iPSCs) to replace dopamine-producing neurons destroyed by Parkinson’s disease. Such cells not only survive the grafting procedure and manufacture dopamine, but send out their branching fibers through the neural tissue to make distant connections in the brain, just like their naturally-occurring counterparts. Credit: […]

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New Tool To Create Ear Hair Cells Lost Due to Aging or Noise

[ad_1] According to a new study, scientists have uncovered a single master gene that programs ear hair cells into either outer or inner ones, overcoming a major hurdle that had prevented the development of these cells to restore hearing. ‘We have overcome a major hurdle’ to restore hearing, investigators say. Gene discovery allows the production […]

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Damaged Liver Tissue Restored Faster Than Ever With Cellular Regeneration Therapy

[ad_1] Liver cells were partially reprogrammed into younger cells (red) using Yamanaka factors (white). The cell nuclei (blue) and cytoskeletal proteins (green) are also shown. Credit: Salk Institute Salk scientists improve liver regeneration in mice, which could lead to new treatments for liver disease. Mammals can’t typically regenerate organs as efficiently as other vertebrates, such […]

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Scientists Create First Comprehensive Map of Human Blood Stem Cell Development

[ad_1] Human blood stem cells emerging from specialized endothelial cells in the wall of an embryonic aorta. UCLA scientists’ confirmation of this process clarifies a longstanding controversy about the stem cells’ cellular origin. Credit: Hanna Mikkola Lab/UCLA, Katja Schenke-Layland Lab/University of Tübingen, Nature UCLA scientists and colleagues have created a first-of-its-kind roadmap that traces each […]

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MIT Scientists Develop New Regenerative Drug That Reverses Hearing Loss

[ad_1] These images show cellular regeneration, in pink, in a preclinical model of sensorineural hearing loss. The control is on the left and the right has been treated. Credit: Hinton AS, Yang-Hood A, Schrader AD, Loose C, Ohlemiller KK, McLean WJ. MIT spinout Frequency Therapeutics’ drug candidate stimulates the growth of hair cells in the […]

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Old Skins Cells Reprogrammed To Regain Youthful Function

[ad_1] Findings could lead to targeted approach for treating aging. Research from the Babraham Institute has developed a method to ‘time jump’ human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function. Work by researchers in the Institute’s Epigenetics research program has been able to partly restore […]

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Newborn Cells in the Epileptic Brain Provide a Potential Target for Anti-Seizure Medications

[ad_1] Altered cells create an electrical “fire” in patients with epilepsy. Credit: BioRender illustration by Aswathy Ammothumkandy/Bonaguidi Lab/USC Stem Cell Over the years, everyone loses a few brain cells. A study led by scientists from USC Stem Cell and the USC Neurorestoration Center presents evidence that adults can replenish at least some of what they’ve […]

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